Prevalence of serum antibodies to caudate nucleus in autistic children

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Prevalence of serum antibodies to caudate nucleus in autistic children.

Autism may involve autoimmunity to brain. We studied regional distribution of antibodies to rat caudate nucleus, cerebral cortex, cerebellum, brain stem and hippocampus. The study included 30 normal and 68 autistic children. Antibodies were assayed by immunoblotting. Autistic children, but not normal children, had antibodies to caudate nucleus (49% positive sera), cerebral cortex (18% positive ...

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INTRODUCTION Autism is a severe neurodevelopmental disorder characterized by impaired communication, social interaction and imagination that is often accompanied by repetitive and stereotyped behavior. It develops before the 36 month of age and persists into adulthood causing life long disability. The prevalence of autism has surged in recent years. The etiology and pathogenesis of autism is no...

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Prevalence of serum antibodies to TORCH infection in the first trimester of the pregnancy in Kashan, Iran

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Metabolic Recovery in Caudate Nucleus

I n 3 children who had undergone cerebral hemispherectomy (hemidecortication) between the ages of 1 year 5 months and 4 years for the alleviation of intractable epilepsy, cerebral glucose utilization was studied serially with positron emission tomography. Three to 7 months after hemispherectomy, glucose utilization i n the caudate nuclei on the side of hemispherectomy had decreased to below pre...

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ژورنال

عنوان ژورنال: Neuroscience Letters

سال: 2004

ISSN: 0304-3940

DOI: 10.1016/j.neulet.2003.10.026